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| Section | Weight | Objectives |
|---|---|---|
| Dimensions of Care | 50% | - Chronic Care - Assessment and Diagnosis - Acute Care - Health Promotion and Illness Prevention |
| Physician Activities | 50% | - Management - Professional Behaviours - Communication - Psychosocial Aspects |
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NEW QUESTION # 253
A 79-year-old woman presents to the Emergency Department with sudden-onset severe chest and back pain that started 1 hour ago. She has a history of hypertension and looks unwell. Her vital signs are as follows:
blood pressure 168/108 mm Hg, heart rate 110/min, respiratory rate 22/min, temperature 36.7°C. Findings of a physical examination of the chest and abdomen are normal. An urgent computed tomography (CT) scan of the chest and abdomen shows an aortic dissection extending from the descending thoracic aorta to the upper abdominal aorta. The branches of the abdominal aorta are patent. Following initial resuscitation, which one of the following is the best next step?
Answer: A
Explanation:
This patient has a Stanford type B aortic dissection , involving the descending thoracic aorta distal to the left subclavian artery, with no evidence of branch vessel compromise or rupture. MCCQE objectives emphasize that uncomplicated type B dissections are managed medically , whereas type A dissections (ascending aorta) require urgent surgical repair.
The immediate priority is to reduce shear stress on the aortic wall by controlling heart rate and blood pressure
. Intravenous beta-blockers such as labetalol or esmolol are first-line therapy. The goal is to reduce heart rate to approximately 60 bpm and lower systolic blood pressure to 100-120 mm Hg. This decreases the force of left ventricular contraction (dP/dt), limiting propagation of the dissection.
Endovascular or open repair is reserved for complicated cases (e.g., malperfusion, rupture, refractory pain, uncontrolled hypertension). Anticoagulation with heparin is contraindicated due to bleeding risk. Observation alone without blood pressure control is inappropriate.
Therefore, intravenous labetalol is the best next step.
NEW QUESTION # 254
A 68-year-old man presents with a 3-day history of multiple tender joints. On examination, he has a temperature of 38.2°C and swelling and redness of his left large toe. Which one of the following is the most likely diagnosis?
Answer: B
Explanation:
This patient presents with acute onset of joint pain, fever, and classic involvement of the first metatarsophalangeal joint (podagra) with swelling and erythema. MCCQE objectives emphasize recognizing the characteristic presentation of crystal-induced arthropathy , particularly gout. Gout commonly affects older men and presents with sudden, severe monoarthritis, often involving the great toe. Systemic symptoms such as low-grade fever may occur during acute attacks.
Viral arthritis typically causes symmetric polyarthritis without marked erythema of a single joint.
Osteoarthritis presents with chronic, non-inflammatory joint pain and minimal warmth or redness. Psoriatic arthritis is usually associated with psoriasis, nail pitting, or dactylitis. Rheumatoid arthritis typically presents as chronic, symmetric small-joint polyarthritis rather than acute podagra.
Although this patient reports multiple tender joints, the prominent inflamed great toe is classic for gout, and polyarticular involvement can occur, especially in older individuals. Diagnosis is ideally confirmed by joint aspiration showing monosodium urate crystals. Initial management includes NSAIDs, colchicine, or corticosteroids.
NEW QUESTION # 255
A 3.5-year-old girl has developed a stutter in the last 3 months. She repeats whole words several times before finishing a sentence. Her paternal uncle had a severe stuttering issue as a child. She has reached the developmental milestones for her age. Her new sibling was born 4 months ago. Which one of the following is the best next step?
Answer: C
Explanation:
This presentation describesnormal developmental dysfluency, which typically occurs between ages 2-5 and often worsens duringtimes of stress or change, such as a new sibling. It is characterized byword repetition and does not require intervention unless it persists >6 months, worsens, or causes distress.
Toronto Notes 2023 - Pediatrics, "Developmental and Behavioral Pediatrics" Section:
"Developmental stuttering is common between 2-5 years and often resolves without intervention.
Reassurance is appropriate unless there are signs of persistent or severe stuttering, secondary behaviors, or parental concern." MCCQE1 Objectives (Pediatrics > 78-1: Development and Behavior):
"Candidates must recognize typical patterns of developmental speech dysfluency and differentiate them from pathological speech disorders. Observation and reassurance are often the appropriate initial step." Because the child is otherwise developing normally and the onset coincides with a known psychosocial stressor,reassuranceis the most appropriate step. Formal speech or behavioral therapy is not indicated at this time.
NEW QUESTION # 256
A mumps outbreak is occurring in your community, with higher attack rates among post-secondary students.
Which one of the following is the most effective intervention?
Answer: C
Explanation:
Mumps is a contagious viral illness spread by respiratory droplets, with transmission occurring from shortly before symptom onset through the early symptomatic period. MCCQE objectives in outbreak management emphasize using effective, feasible source control measures that reduce onward transmission. The most effective intervention listed is exclusion (isolation) of symptomatic clinical cases from school and workplace during the infectious period, because symptomatic individuals are the main identifiable sources of spread and removal from congregate settings directly reduces contact rates and secondary cases.
Antivirals are not standard, effective therapy for mumps and do not control outbreaks. Excluding asymptomatic contacts before symptoms develop is generally less effective and often impractical, because many contacts will never become ill and transmission may already occur before recognition; blanket exclusion can also cause major disruption with limited incremental benefit. Closing an entire post-secondary institution is a high-impact measure with uncertain added benefit compared with targeted case exclusion and is typically reserved for extreme circumstances. Immunoglobulin is not an effective post-exposure prophylaxis for mumps. Therefore, isolating/excluding clinical cases is the best and most effective intervention among the options.
NEW QUESTION # 257
A 26-year-old woman, gravida 2, para 1, presents with a positive pregnancy test. Her previous pregnancy was associated with preeclampsia, and she delivered a 1000 g boy at 34 weeks' gestation. Her blood pressure is 130
/86 mm Hg. Which one of the following is the best recommendation for this pregnancy?
Answer: A
Explanation:
Accurate dating is critical in pregnancies at high risk for preeclampsia and intrauterine growthrestriction. First- trimester ultrasound is used to establish gestational age, which guides monitoring and interventions.
Toronto Notes 2023 - Obstetrics, High-Risk Pregnancy:
"In women with a history of preeclampsia, early and accurate dating allows for appropriate fetal surveillance and timely delivery." MCCQE1 Objectives - Obstetrics > Prenatal Care:
"Candidates should recognize the importance of accurate pregnancy dating in high-risk pregnancies." Prophylactic labetalol (E) is not indicated in normotensive patients. Genetic testing (A, B) is not appropriate unless additional risk factors are present. Bed rest (D) is not evidence-based for preeclampsia prevention.
NEW QUESTION # 258
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