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| Section | Objectives |
|---|---|
| Physician Activities | - Communication
|
| Dimensions of Care | - Acute Care
|
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NEW QUESTION # 237
A 57-year-old man presents with low back pain. Radiographs of the lumbar spine show a narrowed disk space at L4-L5, anterior osteophyte formation at this level, and sclerosis of the L4-L5 end plates. Which one of the following is the most likely diagnosis?
Answer: D
Explanation:
The radiographic triad of disc space narrowing, anterior osteophyte formation, and end-plate sclerosis is classic for degenerative disc disease (lumbar spondylosis). Age-related degeneration leads to disc desiccation and loss of disc height, increasing mechanical stress at vertebral end plates and facet joints. This stimulates reactive bone changes, producing osteophytes and sclerosis. These findings fit a chronic, mechanical cause of low back pain.
Osteomyelitis more often shows end-plate erosion/irregularity with disc space loss plus systemic features (fever, elevated inflammatory markers) and may progress rapidly. Prostate metastases typically cause sclerotic lesions in vertebral bodies without isolated disc space narrowing and osteophytes. Paget disease produces bony expansion, cortical thickening, and coarse trabeculation rather than focal disc degeneration changes.
Spondylolysis/spondylolisthesis is suggested by pars defects and vertebral slippage, not primarily by disc narrowing with osteophytes and end-plate sclerosis. MCCQE objectives emphasize interpreting common spine imaging patterns and distinguishing degenerative disease from infection, malignancy, and structural instability.
NEW QUESTION # 238
An 85-year-old man is transferred from an acute care hospital to your long-term care (LTC) facility. He has a fever, fatigue, myalgia, and malaise. His test result is positive for influenza A virus. Two other residents and 1 LTC staff member have experienced the same symptoms. Which one of the following is the best next step to prevent further infections at the LTC facility?
Answer: B
NEW QUESTION # 239
An 83-year-old woman presents to your office with a 2-day history of confusion. Her past medical history is significant for lung cancer, and she is being treated with radiation. On physical examination, she is euvolemic.
Her blood work reveals a serum sodium of 118 mmol/L (135-140) as compared with 134 mmol/L (8 days ago). Which one of the following will be most helpful in establishing the cause of her laboratory abnormality?
Answer: E
Explanation:
Comprehensive and Detailed Explanation:
Hyponatremia in a patient with lung cancer and euvolemia strongly suggests syndrome of inappropriate antidiuretic hormone secretion (SIADH), especially from small cell carcinoma. Serum osmolality is the best initial test to confirm hypotonic hyponatremia and distinguish true hyponatremia from pseudohyponatremia or other causes.
Toronto Notes 2023 - Endocrinology, "Hyponatremia":
"Serum osmolality helps classify hyponatremia as hypotonic, isotonic, or hypertonic. SIADH typically causes hypotonic hyponatremia in euvolemic patients." MCCQE1 Objectives (Endocrinology > 37-1: Electrolyte Disorders):
"Candidates must evaluate the type and cause of hyponatremia using clinical status and laboratory tests including serum osmolality." Urine sodium (B) is useful after confirming hypotonicity. PTHrP (E) is associated with hypercalcemia of malignancy, not hyponatremia. Urinalysis (A) and CrCl (D) are less directly informative.
NEW QUESTION # 240
A 16-year-old boy presents to the emergency department with a 12-hour history of fever and rigors. He has sickle cell anemia. On examination, his vital signs include the following:
Heart rate
110/min (60-100)
Respiratory rate
20/min (12-18)
Temperature
38.8 °C, oral (36.5-37.5)
Which one of the following places this patient at risk for sepsis?
Answer: D
Explanation:
Patients with sickle cell anemia often develop functional asplenia due to repeated splenic infarction. The spleen plays a critical role in clearing encapsulated organisms such as Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis. Functional asplenia significantly increases the risk of overwhelming sepsis.
Toronto Notes 2023 - Hematology, "Sickle Cell Disease":
"Functional asplenia is common in sickle cell disease and increases the risk for sepsis due to impaired clearance of encapsulated bacteria." MCCQE1 Objectives (Pediatrics > 77-2: Hematology):
"Candidates must recognize that patients with functional asplenia are at increased risk for sepsis and require prompt evaluation for fever." Neutrophil dysfunction (B) and immunoglobulin deficiency (C) are not typical features of sickle cell anemia.
Chronic anemia (D) and iron overload (E) do not directly increase sepsis risk.
NEW QUESTION # 241
An infrastructure engineer in an AI factory has successfully replaced a power supply unit on an NVIDIA DGX H100. After installation, both the IN and OUT LEDs on the new power supply illuminate solid green.
Which NVSM CLI command should the engineer use to quickly verify the overall system status and ensure it is operating as expected?
Answer: B
Explanation:
Comprehensive and Detailed Explanation:
The NVIDIA System Management (NVSM) tool is the definitive CLI utility for monitoring the health of DGX platforms. While replacing a PSU (Power Supply Unit) is a common maintenance task, verifying that the new component is correctly integrated into the system's health model is mandatory. While `nvsm show power` would provide specific data regarding wattage and voltage for the PSU, the most comprehensive way to ensure the replacement hasn ' t caused secondary issues or that the system hasn ' t remained in a " Degraded
" state is to run `nvsm show health`. This command performs a global check across all subsystems: GPUs, NVLink switches, storage, fans, and power. If the PSU replacement was successful and the system is back to full redundancy, `nvsm show health` will return a " Healthy " status. In an AI factory setting, where DGX H100 nodes pull significant power, ensuring that all 6 PSUs (in an N+N or N+1 configuration) are not only physically green but logically acknowledged by the Baseboard Management Controller (BMC) is critical for preventing unexpected shutdowns during high-load training iterations.
NEW QUESTION # 242
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