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Medical Council of Canada MCCQE Exam Syllabus Topics:

SectionWeightObjectives
Dimensions of Care50%- Health Promotion and Illness Prevention
- Acute Care
- Chronic Care
- Assessment and Diagnosis
Physician Activities50%- Management
- Professional Behaviours
- Communication
- Psychosocial Aspects

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Medical Council of Canada MCCQE Part 1 Exam Sample Questions (Q343-Q348):

NEW QUESTION # 343
A 62-year-old woman is taken to the operating room for an elective laparoscopic cholecystectomy. Induction of anesthesia triggers a severe hypertensive crisis that ultimately resolves after administration of a 5 mg bolus of phentolamine.
Which one of the following is most consistent with this presentation?

Answer: B

Explanation:
This presentation is classic for an undiagnosed pheochromocytoma, which causes episodic or crisis-level hypertension due to excess catecholamines. Anesthesia or surgical manipulation can trigger massive catecholamine release, leading to hypertensive crisis. Phentolamine, an alpha-blocker, is the appropriate treatment.
Toronto Notes 2023 - Endocrinology, Pheochromocytoma:
"Pheochromocytomas may precipitate hypertensive crises during surgery. Elevated plasma catecholamines and urinary metanephrines confirm diagnosis." MCCQE1 Objectives - Internal Medicine > Endocrinology:
"Candidates should suspect pheochromocytoma in perioperative hypertensive crises and confirm with plasma or urine catecholamines/metanephrines." Low metanephrines (E) would argue against pheochromocytoma. TSH (A), cortisol (D), and renin (C) are unrelated to acute intraoperative hypertensive episodes of this nature.


NEW QUESTION # 344
You receive a note from a pharmacist about your 82-year-old patient who is taking oxycodone extended- release 20 mg 3 times daily for spinal stenosis. The pharmacist suggests that you consider tapering the medication. Your patient has been taking his current dosage for 1 year. When you saw him a month ago, he was functioning well with no adverse effects from the medication. Which one of the following is the best next step?

Answer: D

Explanation:
Long-term opioid therapy requires ongoing assessment of benefits, risks, function, adverse effects, and safety, particularly in older adults. MCCQE objectives emphasize regular reassessment before making changes to chronic controlled medications. Although the pharmacist has appropriately raised concern about prolonged opioid use, the patient was reported one month ago to be functioning well without adverse effects.
The appropriate next step is to reassess the patient directly-including pain control, functional status, cognition, fall risk, constipation, signs of misuse, and overall goals of care-before altering therapy.
Automatic dose reduction without evaluation may destabilize pain control. Immediate referral to a specialist is unnecessary if the patient is stable and well managed. Adjunct therapies such as physiotherapy may be considered but should not replace proper reassessment.
Shared decision-making is essential. If reassessment reveals limited benefit, adverse effects, or safety concerns, a gradual taper can then be discussed. Clinical decisions regarding opioids should be individualized rather than based solely on duration of use.


NEW QUESTION # 345
A mother brings her 4-week-old daughter to your office because she is concerned about the lesion shown in the attached image. Which one of the following is the most appropriate advice to give the mother?

Answer: C

Explanation:
In a 4-week-old infant, a common vascular lesion such as a nevus simplex ("salmon patch") or a superficial infantile hemangioma is a frequent benign finding. Nevus simplex lesions are flat, pink-red patches commonly located on the eyelids, glabella, or nape of the neck and typically fade spontaneously over the first
1-2 years of life. Superficial infantile hemangiomas may initially enlarge but later undergo spontaneous involution during early childhood. In the absence of concerning features (rapid ulceration, functional impairment, large segmental distribution, or associated anomalies), reassurance and observation are appropriate.
There is no indication of trauma requiring child protective services, nor signs of a bleeding disorder. These common neonatal vascular lesions are not associated with increased melanoma risk. Routine dermatology referral is unnecessary unless the lesion is atypical or complicated.
MCCQE objectives emphasize distinguishing benign neonatal skin findings from pathology, providing parental reassurance, and avoiding unnecessary investigations or referrals while recognizing features that would warrant further evaluation.


NEW QUESTION # 346
A 1-week-old boy born at full term is brought by his parents to the office with a 2-day history of eye swelling and watery discharge. This morning, the discharge became thick and yellow. On physical exam, he is afebrile and fussy with bilateral eyelid edema, purulent discharge, and erythematous conjunctivae. After taking appropriate cultures of the eyes, which one of the following is the best next step?

Answer: D

Explanation:
Comprehensive and Detailed Explanation:
This neonate likely has gonococcal conjunctivitis, which typically presents 2-5 days after birth with bilateral purulent discharge and swelling. This is an emergency due to the risk of corneal perforation. Empiric IV antibiotics and hospital admission are indicated.
Toronto Notes 2023 - Pediatrics, Neonatal Infections:
"Neonatal conjunctivitis within the first 1-2 weeks should raise suspicion for gonococcal or chlamydial infection. Gonorrhea requires urgent IV antibiotics and hospitalization." MCCQE1 Objectives - Pediatrics > Neonatal Infection:
"Candidates must recognize neonatal conjunctivitis and initiate empiric treatment while awaiting culture results." Lacrimal massage (E) and warm compresses (D) are used for nasolacrimal duct obstruction. Oral or topical antibiotics (B, C) are insufficient for suspected gonococcal infection.


NEW QUESTION # 347
A young man and woman who are in a relationship present to the office for prenatal counselling. During the visit, you observe that the man's lips appear as shown in the referenced photo.

[Image shows grouped vesicular lesions on erythematous base affecting the lips-classic for herpes labialis (HSV-1).] Which one of the following is the best advice?

Answer: A

Explanation:
The patient shows signs of herpes labialis (HSV-1), which can transmit genital herpes via oral sex. This poses a risk to the fetus if maternal infection occurs during pregnancy, especially near delivery. Preventing new genital HSV infection during pregnancy is critical.
Toronto Notes 2023 - Obstetrics:
"HSV-1 can cause genital herpes via oral-genital transmission. Avoid oral sex during outbreaks in pregnancy to prevent primary maternal infection." MCCQE1 Objectives (Obstetrics > 80-3: Infectious Disease in Pregnancy):
"Candidates must understand the importance of preventing new HSV infection during pregnancy and counsel appropriately." Culture (A) is not useful unless symptomatic. Serology (B) is not needed in this context. Cesarean (D) is not indicated unless active genital lesions at delivery. Acyclovir (C) is for infected mothers or near delivery.


NEW QUESTION # 348
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