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| Section | Objectives |
|---|---|
| Topic 1: Dimensions of Care | - Acute Care
|
| Topic 2: Physician Activities | - Assessment
|
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NEW QUESTION # 122
A 59-year-old woman is referred to you because of a 2-month history of left nipple discharge. She is otherwise healthy and is not on any medication. There are no palpable lesions on breast examination. She is able to express a small amount of blood-tinged liquid from her breast. Which one of the following would be the best next step?
Answer: E
Explanation:
Spontaneous, unilateral, blood-tinged nipple discharge in a postmenopausal woman is considered pathologic and warrants imaging to rule out intraductal pathology including malignancy. The best initial test is diagnostic mammography, often with ultrasound if indicated.
Toronto Notes 2023 - Breast Disorders:
"Unilateral, spontaneous, bloody nipple discharge should be evaluated with mammography and targeted ultrasound. Further tests such as MRI or duct excision are based on findings." MCCQE1 Objectives (Gynecology > 81-1: Breast Conditions):
"Candidates must recognize red flags for breast malignancy and apply appropriate initial diagnostic imaging." Serum prolactin (C) is indicated in galactorrhea. Galactography (D) and MRI (E) are second-line. Biopsy (A) is premature without imaging.
NEW QUESTION # 123
A 34-year-old man presents to your office with a 2-week history of headaches and double vision when he looks to the right. On physical examination, you note that he is unable to gaze laterally with his right eye.
Which one of the following cranial nerves is most likely affected?
Answer: E
Explanation:
The inability to gaze laterally with the right eye indicates dysfunction of the right lateral rectus muscle , which is innervated by cranial nerve VI (the abducens nerve). The primary action of the lateral rectus muscle is abduction of the eye (movement away from the midline). Damage to the abducens nerve results in an inability to abduct the affected eye, leading to horizontal diplopia that worsens when looking toward the side of the lesion.
MCCQE objectives emphasize understanding cranial nerve function and localization. The oculomotor nerve (CN III) controls most extraocular movements but not lateral rectus. Trochlear nerve (CN IV) innervates the superior oblique muscle, affecting downward and inward gaze. The optic nerve (CN II) is responsible for vision, not eye movement. The trigeminal nerve (CN V) provides facial sensation and mastication motor function.
Headache with a new sixth nerve palsy may raise concern for increased intracranial pressure or intracranial pathology, as CN VI is vulnerable due to its long intracranial course. Further evaluation is warranted.
NEW QUESTION # 124
A 42-year-old woman, gravida 2, para 2, aborta 0, comes to the office for the first time. She reports a 6-month history of thirst, urinary frequency, and recurrent vaginitis. Aside from a BMI of 28, her physical examination findings are unremarkable. She takes no medications. Which one of the following would support the most likely diagnosis?
Answer: D
Explanation:
This patient's symptoms of polyuria, polydipsia, and recurrent vaginitis are classic for type 2 diabetes mellitus (T2DM) . Recurrent vaginal candidiasis occurs due to glycosuria promoting yeast overgrowth. MCCQE objectives emphasize identifying risk factors and historical features supporting diabetes. A prior delivery of a macrosomic infant ( > 4000-4500 g) is strongly associated with gestational diabetes mellitus (GDM) , which significantly increases the future risk of developing T2DM. Therefore, a history of macrosomia supports undiagnosed or previous gestational hyperglycemia and increases suspicion for current diabetes.
High-risk sexual behaviors relate to sexually transmitted infections, not diabetes. Family history of hypertension is a cardiovascular risk factor but does not specifically support diabetes. Recent antibiotic use may predispose to candidiasis but would not explain polyuria and polydipsia. Dry eyes are more suggestive of autoimmune conditions (e.g., Sjogren syndrome).
Thus, prior delivery of a macrosomic newborn strengthens the likelihood that her current symptoms are due to type 2 diabetes mellitus.
NEW QUESTION # 125
A young man and woman who are in a relationship present to the office for prenatal counselling. During the visit, you observe that the man ' s lips appear as shown in the referenced photo.
[Image shows grouped vesicular lesions on erythematous base affecting the lips-classic for herpes labialis (HSV-1).] Which one of the following is the best advice?
Answer: C
Explanation:
The patient shows signs of herpes labialis (HSV-1), which can transmit genital herpes via oral sex. This poses a risk to the fetus if maternal infection occurs during pregnancy, especially near delivery. Preventing new genital HSV infection during pregnancy is critical.
Toronto Notes 2023 - Obstetrics:
"HSV-1 can cause genital herpes via oral-genital transmission. Avoid oral sex during outbreaks in pregnancy to prevent primary maternal infection." MCCQE1 Objectives (Obstetrics > 80-3: Infectious Disease in Pregnancy):
"Candidates must understand the importance of preventing new HSV infection during pregnancy and counsel appropriately." Culture (A) is not useful unless symptomatic. Serology (B) is not needed in this context. Cesarean (D) is not indicated unless active genital lesions at delivery. Acyclovir (C) is for infected mothers or near delivery.
NEW QUESTION # 126
An 85-year-old man is transferred from an acute care hospital to your long-term care (LTC) facility. He has a fever, fatigue, myalgia, and malaise. His test result is positive for influenza A virus. Two other residents and 1 LTC staff member have experienced the same symptoms. Which one of the following is the best next step to prevent further infections at the LTC facility?
Answer: B
Explanation:
During an outbreak in a long-term care facility, prompt control measures include keeping symptomatic staff at home to prevent spread. Staff are often vectors of infection, and exclusion is a key public health intervention.
Toronto Notes 2023 - Infectious Diseases, "Infection Control and Prevention":
"During influenza outbreaks in institutional settings, exclusion of symptomatic staff is critical to controlling spread." MCCQE1 Objectives (Population Health > 63-2: Outbreak Management):
"Candidates must understand outbreak control, including staff exclusion, cohorting, and surveillance in congregate settings." Vaccination (B) is preventive but not immediately effective during an outbreak. Masking and visitor vaccination are supportive but secondary measures.
NEW QUESTION # 127
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